Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 6/20 | 0.62 |
| ▸ | MMP9 | P14780 | 5/20 | 0.62 |
| ▸ | MMP2 | P08253 | 4/20 | 0.62 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | ADAM33 | Q9BZ11 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627379 | 0.85 | MMP2 (0.51) | ADAM17MMP9MMP2MMP1 | |
| SCHEMBL6626860 | 0.83 | MMP1 (0.55) | ADAM17MMP9MMP2MMP13MMP1 | |
| SCHEMBL7425875 | 0.83 | ADAM17 (0.68) | ADAM17MMP9MMP2MMP13MMP1 | |
| SCHEMBL7428024 | 0.83 | ADAM17 (0.68) | ADAM17MMP9MMP2MMP13MMP1 | |
| SCHEMBL27517827 | 0.76 | KCNH2 (0.48) | ADAM17MMP13LTA4HLMNARAB9A | |
| SCHEMBL6628455 | 0.76 | MMP9 (1.00) | ADAM17MMP9MMP2MMP13MMP1 | |
| SCHEMBL6629399 | 0.75 | MMP2 (0.75) | ADAM17MMP9MMP2MMP13MMP1 | |
| SCHEMBL7427250 | 0.74 | ADAM17 (0.67) | ADAM17MMP9MMP2MMP13MMP1 | |
| Trifluoroacetic Acid SCHEMBL6628306 | 0.73 | ADAM17 (0.41) | ADAM17MMP9MMP2MMP1 | |
| SCHEMBL17315811 | 0.73 | ADAM17 (0.68) | ADAM17MMP9MMP2MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027332-B1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2004-05-26 | — | — | EP | claimed |