Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625140 | 1.00 | MAPT (0.56) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL6624634 | 0.78 | ALDH1A1 (0.58) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL6624638 | 0.78 | ALDH1A1 (0.58) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL30885138 | 0.76 | MAPT (0.60) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL21378473 | 0.75 | POLB (0.54) | MAPTKDM4EALDH1A1KMT2APOLB | |
| SCHEMBL21378474 | 0.75 | POLB (0.54) | MAPTKDM4EALDH1A1KMT2APOLB | |
| Bicarbonate SCHEMBL3555865 | 0.75 | MAPT (0.63) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL6625925 | 0.74 | MAPT (0.46) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL6625930 | 0.74 | MAPT (0.46) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL607498 | 0.74 | USP2 (0.58) | MAPTKDM4EALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116417-A1 | Thiohydantoins and use thereof for treating diabetes | LABORATOIRES FOURNIER SA (FR) | 2004-06-17 | — | — | US | disclosed |
| EP-1373219-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002081453-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER SA (FR) | 2002-10-17 | — | — | WO | disclosed |