Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625930 | 1.00 | MAPT (0.46) | MAPTALDH1A1NPSR1RECQLKMT2A | |
| SCHEMBL6624638 | 0.84 | ALDH1A1 (0.58) | MAPTALDH1A1GAAKDM4ENPC1 | |
| SCHEMBL6624634 | 0.84 | ALDH1A1 (0.58) | MAPTALDH1A1GAAKDM4ENPC1 | |
| SCHEMBL27583633 | 0.82 | MAPT (0.43) | MAPTALDH1A1NPSR1RECQLKMT2A | |
| SCHEMBL6626495 | 0.78 | RORC (0.45) | MAPTALDH1A1NPSR1RECQLKMT2A | |
| SCHEMBL6626492 | 0.78 | RORC (0.45) | MAPTALDH1A1NPSR1RECQLKMT2A | |
| SCHEMBL5221253 | 0.76 | MAPT (0.51) | MAPTALDH1A1NPSR1KMT2AGAA | |
| SCHEMBL6625140 | 0.74 | MAPT (0.56) | MAPTALDH1A1KMT2AKDM4ERAB9A | |
| SCHEMBL6628495 | 0.74 | MAPT (0.56) | MAPTALDH1A1KMT2AKDM4ERAB9A | |
| SCHEMBL6625138 | 0.73 | MAPT (0.42) | MAPTALDH1A1NPSR1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116417-A1 | Thiohydantoins and use thereof for treating diabetes | LABORATOIRES FOURNIER SA (FR) | 2004-06-17 | — | — | US | disclosed |
| EP-1373219-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002081453-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER SA (FR) | 2002-10-17 | — | — | WO | disclosed |