Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 16/20 | 0.69 |
| ▸ | MMP13 | P45452 | 13/20 | 0.69 |
| ▸ | ADAM17 | P78536 | 13/20 | 0.69 |
| ▸ | MMP1 | P03956 | 13/20 | 0.69 |
| ▸ | MMP2 | P08253 | 5/20 | 0.63 |
| ▸ | MMP8 | P22894 | 2/20 | 0.63 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | BMP1 | P13497 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3946389 | 0.99 | MMP9 (0.68) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL3947833 | 0.91 | MMP9 (0.77) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL6501401 | 0.90 | MMP9 (0.65) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL6498854 | 0.88 | MMP9 (0.62) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL13643228 | 0.86 | MMP9 (0.75) | MMP9MMP13MMP1MMP2MMP8 | |
| SCHEMBL13643229 | 0.86 | MMP9 (0.75) | MMP9MMP13MMP1MMP2MMP8 | |
| SCHEMBL3946148 | 0.85 | MMP9 (0.77) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL3940026 | 0.85 | MMP9 (0.62) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL26775210 | 0.83 | MMP9 (0.66) | MMP9MMP13MMP2MMP8BMP1 | |
| SCHEMBL6625851 | 0.82 | MMP13 (1.00) | MMP9MMP13ADAM17MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144368-B1 | ACETYLENIC ALPHA-AMINO ACID-BASED SULFONAMIDE HYDROXAMIC ACID TACE INHIBITORS | WYETH CORP (US) | 2004-07-14 | — | — | EP | claimed |