SCHEMBL13643228

SCHEMBL13643228

COc1ccc(S(=O)(=O)N(Cc2cccnc2)[C@H](C)C(=O)NO)cc1

nearest known ligand 0.75

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 8/20 0.75
MMP2 P08253 7/20 0.75
BMP1 P13497 12/20 0.68
MMP8 P22894 4/20 0.65
MMP13 P45452 4/20 0.65
MMP1 P03956 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13643229 1.00 MMP9 (0.75) MMP9MMP2BMP1MMP8MMP13
SCHEMBL29350980 0.90 MMP9 (0.80) MMP9MMP2MMP8MMP13
SCHEMBL13253256 0.90 MMP9 (0.80) MMP9MMP2MMP8MMP13
SCHEMBL3468445 0.90 MMP9 (0.80) MMP9MMP2MMP8MMP13
SCHEMBL3468444 0.90 MMP9 (0.80) MMP9MMP2MMP8MMP13
Hydrochloric Acid SCHEMBL7351872 0.89 MMP9 (0.78) MMP9MMP2MMP8MMP13
Hydrochloric Acid SCHEMBL3158786 0.89 MMP9 (0.78) MMP9MMP2MMP8MMP13
Hydrochloric Acid SCHEMBL3158778 0.89 MMP9 (0.78) MMP9MMP2MMP8MMP13
SCHEMBL13639195 0.89 MMP9 (0.79) MMP9MMP2BMP1MMP8MMP13
SCHEMBL9168780 0.89 MMP9 (0.79) MMP9MMP2BMP1MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357139-A1 SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS Artizan Biosciences, Inc. 2023-11-09 US disclosed
US-20120282180-A1 Compounds with Matrix-Metalloproteinase Inhibitory Activity and Imaging Agents Thereof SIEMENS MEDICAL SOLUTIONS USA, INC. 2012-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120282180-A1 Compounds with Matrix-Metalloproteinase Inhibitory Activity and Imaging Agents Thereof MMP1, MMP17, MMP25 MMP9 4/4885MMP2 16/4885BMP1 638/4885
US-20230357139-A1 SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS FABP2, APC, SI MMP9 612/4885MMP2 166/4885BMP1 3685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.