Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 0.53 |
| ▸ | MAOB | P27338 | 11/20 | 0.53 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.52 |
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319226 | 0.97 | BAZ2B (0.56) | MAOAMAOBBAZ2BPRKCIALDH1A1 | |
| SCHEMBL7389121 | 0.90 | MAPT (0.49) | MAOBBAZ2BPGRESR1CHRM2 | |
| SCHEMBL30821349 | 0.90 | MAPT (0.49) | MAOBBAZ2BPGRESR1CHRM2 | |
| SCHEMBL8318501 | 0.84 | MAOA (0.53) | MAOAMAOBBAZ2BPRKCIPGR | |
| SCHEMBL19132617 | 0.84 | MAOA (0.50) | MAOAMAOBBAZ2BPRKCIMAPK14 | |
| SCHEMBL7953934 | 0.83 | MAOB (0.55) | MAOAMAOBBAZ2BPRKCIMAPK14 | |
| SCHEMBL8319221 | 0.82 | BAZ2B (0.54) | MAOAMAOBBAZ2BPRKCI | |
| SCHEMBL17996957 | 0.82 | BAZ2B (0.57) | MAOAMAOBBAZ2BPRKCIMAPK14 | |
| SCHEMBL9261533 | 0.82 | ALOX15 (0.56) | PGRESR1CHRM2ADORA3AR | |
| SCHEMBL6628767 | 0.81 | MAOA (0.54) | MAOAMAOBBAZ2BPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338740-A | Angiotensin II receptor antagonists | PFIZER INC. (US) | 1994-08-16 | — | — | US | disclosed |