SCHEMBL5485052

SCHEMBL5485052

NC(=O)Oc1ccc2c(c1)CCC2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.55
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
STS P08842 1/20 0.51
ALOX15 P16050 1/20 0.51
TSHR P16473 1/20 0.51
HSD17B10 Q99714 1/20 0.51
NPC1 O15118 6/20 0.48
RAB9A P51151 6/20 0.48
ALDH1A1 P00352 4/20 0.48
MAPT P10636 4/20 0.48
TP53 P04637 1/20 0.48
RXRB P28702 4/20 0.48
RXRA P19793 3/20 0.48
RXRG P48443 3/20 0.48
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA14 Q9ULX7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11653596 0.85 SMN1; SMN2 (0.58) SMN1; SMN2STSALOX15TSHRHSD17B10
SCHEMBL875632 0.83 ALOX15 (0.57) SMN1; SMN2STSALOX15TSHRHSD17B10
SCHEMBL6628767 0.82 MAOA (0.54) MEN1KMT2A
SCHEMBL3896033 0.81 SMN1; SMN2 (0.55) SMN1; SMN2MEN1KMT2ASTSALOX15
SCHEMBL9667577 0.81 SMN1; SMN2 (0.48) SMN1; SMN2STSALOX15TSHRHSD17B10
SCHEMBL17087126 0.81 SMN1; SMN2 (0.55) SMN1; SMN2STSALOX15TSHRHSD17B10
Hydrochloric Acid SCHEMBL12468468 0.81 ALOX15 (0.56) SMN1; SMN2STSALOX15TSHRHSD17B10
SCHEMBL9719992 0.81 ALOX15 (0.59) SMN1; SMN2STSALOX15TSHRHSD17B10
SCHEMBL6890990 0.80 SMN1; SMN2 (0.54) SMN1; SMN2STSALOX15TSHRHSD17B10
SCHEMBL7090466 0.80 SMN1; SMN2 (0.47) SMN1; SMN2MEN1KMT2ASTSALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117242060-A Isoindolinone compounds 蒙特罗萨医疗公司 2023-12-15 CN disclosed
EP-1389606-B1 Separatory agent for enantiomeric isomers comprising a polysaccharide with an indanyl group DAICEL CHEM (JP) 2013-06-05 EP disclosed
US-7156989-B2 Separating agent including polysaccharide derivative having a polycyclic structure DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-01-02 US disclosed
CN-1211322-C Separating agent comprising polysaccharide derivative having polycyclic structure DAICEL CHEM (JP) 2005-07-20 CN disclosed
US-20040065608-A1 Separatory agent comprising polysacciiaride derivative having polycyclic structure DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-08 US disclosed
EP-1389606-A1 SEPARATORY AGENT COMPRISING POLYSACCHARIDE DERIVATIVE HAVING POLYCYCLIC STRUCTURE Daicel Chemical Industries, Ltd. (JP) 2004-02-18 EP disclosed
CN-1462263-A Separatory agent comprising polysaccharide derivative having polycyclic structrue DAICEL CHEM (JP) 2003-12-17 CN disclosed