Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP5 | Q13451 | 3/20 | 0.69 |
| ▸ | FKBP1A | P62942 | 17/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15450996 | 0.90 | FKBP5 (0.76) | FKBP5FKBP1A | |
| SCHEMBL15436075 | 0.82 | FKBP5 (1.00) | FKBP5FKBP1A | |
| SCHEMBL6624244 | 0.82 | FKBP5 (0.70) | FKBP5FKBP1A | |
| SCHEMBL6627612 | 0.81 | FKBP1A (0.57) | FKBP5FKBP1A | |
| SCHEMBL15436148 | 0.78 | FKBP5 (0.69) | FKBP5FKBP1A | |
| SCHEMBL15436127 | 0.77 | FKBP5 (0.50) | FKBP5FKBP1AALDH1A1 | |
| SCHEMBL6625880 | 0.77 | FKBP1A (0.44) | FKBP5FKBP1AALDH1A1 | |
| SCHEMBL6627657 | 0.77 | FKBP1A (0.51) | FKBP5FKBP1A | |
| SCHEMBL15436060 | 0.74 | FKBP5 (1.00) | FKBP5FKBP1A | |
| SCHEMBL16859292 | 0.70 | FKBP5 (0.67) | FKBP5FKBP1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098897-B1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR STIMULATING NEURONAL GROWTH AND ELONGATION | AGOURON PHARMA (US) | 2004-06-09 | — | — | EP | disclosed |
| US-6630472-B1 | Peptidyl-prolyl isomerase inhibitors | PFIZER INC | 2003-10-07 | — | — | US | disclosed |