Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775961 | 0.84 | KMT2A (0.42) | FKBP1AKMT2AL3MBTL1STSFKBP5 | |
| SCHEMBL6785002 | 0.84 | KMT2A (0.41) | FKBP1AKMT2AL3MBTL1STSFKBP5 | |
| SCHEMBL6778841 | 0.83 | KMT2A (0.41) | FKBP1AKMT2AL3MBTL1STSFKBP5 | |
| SCHEMBL6780351 | 0.79 | KMT2A (0.40) | FKBP1AKMT2AL3MBTL1STSJAK2 | |
| SCHEMBL15436127 | 0.78 | FKBP5 (0.50) | FKBP1AKMT2AFKBP5MEN1TSHR | |
| SCHEMBL6628799 | 0.77 | FKBP5 (0.69) | FKBP1AFKBP5ALDH1A1 | |
| SCHEMBL6776517 | 0.73 | FKBP5 (0.45) | FKBP1AKMT2AL3MBTL1FKBP5TSHR | |
| SCHEMBL9977203 | 0.72 | SRC (0.49) | KMT2AL3MBTL1HDAC1HDAC8HDAC6 | |
| Benzylamine SCHEMBL18049727 | 0.72 | KMT2A (0.47) | KMT2AL3MBTL1STSHDAC1JAK2 | |
| SCHEMBL2301209 | 0.71 | KMT2A (0.55) | KMT2AL3MBTL1STSJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098897-B1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR STIMULATING NEURONAL GROWTH AND ELONGATION | AGOURON PHARMA (US) | 2004-06-09 | — | — | EP | disclosed |
| US-6630472-B1 | Peptidyl-prolyl isomerase inhibitors | PFIZER INC | 2003-10-07 | — | — | US | disclosed |
| EP-1098897-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR STIMULATING NEURONAL GROWTH AND ELONGATION | AGOURON PHARMACEUTICALS, INC. (US) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004020-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR STIMULATING NEURONAL GROWTH AND ELONGATION | AGOURON PHARMACEUTICALS, INC. (US) | 2000-01-27 | — | — | WO | disclosed |