Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699112 | 0.80 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL9097481 | 0.78 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL79874 | 0.76 | MAPK1 (0.37) | MAPK1 | |
| SCHEMBL15888456 | 0.76 | MAPK1 (0.37) | MAPK1 | |
| SCHEMBL2456643 | 0.76 | SMYD2 (0.36) | — | |
| SCHEMBL13907170 | 0.74 | CYP3A4 (0.31) | — | |
| SCHEMBL12820837 | 0.74 | CYP3A4 (0.31) | — | |
| SCHEMBL704188 | 0.74 | MAPK1 (0.36) | MAPK1 | |
| SCHEMBL17496700 | 0.73 | SMYD2 (0.33) | — | |
| SCHEMBL2188878 | 0.73 | SMYD2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2948455-B1 | N-ACYL-(3-SUBSTITUTED)-(8-SUBSTITUTED)-5,6-DIHYDRO- [1,2,4]TRIAZOLO[4,3-A]PYRAZINES AS SELECTIVE NK-3 RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR USE IN NK-3 RECEPTOR-MEDIATED DISORDERS | OGEDA S A (FR) | 2017-09-27 | — | — | EP | claimed |
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | claimed |
| WO-2009052507-A1 | BRYOSTATIN ANALOGUES, SYNTHETIC METHODS AND USES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2009-04-23 | — | — | WO | disclosed |