Sugi Predict

Sugi Predict / Compounds / SCHEMBL704188

SCHEMBL704188

SCHEMBL704188

CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.36
▸ CA4 P22748 2/20 0.35
▸ NR1H2 P55055 3/20 0.34
▸ NR1H3 Q13133 3/20 0.34
▸ ALDH1A1 P00352 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ ESR1 P03372 1/20 0.32
▸ ESR2 Q92731 1/20 0.32
▸ POLB P06746 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ SMYD2 Q9NRG4 1/20 0.31
▸ CA12 O43570 1/20 0.31
▸ CA1 P00915 1/20 0.31
▸ CA2 P00918 1/20 0.31
▸ CA7 P43166 1/20 0.31
▸ CA9 Q16790 1/20 0.31
▸ CA14 Q9ULX7 1/20 0.31
▸ ABL1 P00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL79874 0.83 MAPK1 (0.37) MAPK1CA4NR1H2NR1H3ALDH1A1
SCHEMBL15888456 0.83 MAPK1 (0.37) MAPK1CA4NR1H2NR1H3ALDH1A1
SCHEMBL19502569 0.82 TSHR (0.31) —
SCHEMBL25977463 0.82 MAPK1 (0.33) MAPK1CA4ALDH1A1ALOX15ESR1
SCHEMBL18924906 0.79 ALDH1A1 (0.41) MAPK1NR1H2NR1H3ALDH1A1ALOX15
SCHEMBL19720997 0.79 MAPK1 (0.34) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL4835281 0.79 MAPK1 (0.34) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL707572 0.79 MAPK1 (0.34) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL31318429 0.79 MAPK1 (0.34) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL707090 0.79 MAPK1 (0.34) MAPK1ALDH1A1ALOX15ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978019-A Alpha-carbon glycoside based on organic trifluoro borate, synthesis method and application thereof in pharmacy 三峡大学 2025-05-13 — — CN claimed
CN-116120777-A Preparation method of modified silica sol for water-based ink 山东科翰硅源新材料有限公司 2023-05-16 — — CN claimed
CN-112812133-B Alpha, alpha-difluoroallyl organometallic compound and preparation method and application thereof 南京工业大学 2022-03-11 — — CN claimed
CN-112812133-A Alpha, alpha-difluoroallyl organometallic compound and preparation method and application thereof 南京工业大学 2021-05-18 — — CN claimed
WO-2020247927-A1 NOVEL SYSTEMS, METHODS AND COMPOSITIONS FOR THE DIRECT SYNTHESIS OF STICKY ENDED POLYNUCLEOTIDES THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) 2020-12-10 — — WO claimed
CN-111883748-A Method for coating oxide film on surface of lithium ion battery anode powder material 华南理工大学 2020-11-03 — — CN claimed
US-8039049-B2 Treatment of low dielectric constant films using a batch processing system TOKYO ELECTRON LIMITED (JP) 2011-10-18 — — US claimed
US-20110009607-A1 METHOD FOR PREPARING DNA FRAGMENT HAVING STICKY END THE UNIVERSITY OF TOKYO (JP) 2011-01-13 — — US claimed
EP-2270142-A1 METHOD OF PREPARING DNA FRAGMENT HAVING STICKY END The University of Tokyo (JP) 2011-01-05 — — EP claimed
US-7405168-B2 Plural treatment step process for treating dielectric films TOKYO ELECTRON LIMITED (JP) 2008-07-29 — — US claimed
EP-1114065-A1 CELLULOSE MICROFIBRILS WITH MODIFIED SURFACE, PREPARATION METHOD AND USE THEREOF RHODIA CHIMIE (FR) 2001-07-11 — — EP claimed
WO-2000050478-A1 NOVEL FORMULATIONS OF ALKYLLITHIUMS WITH IMPROVED THERMAL STABILITY, PROCESSES TO PRODUCE THESE FORMULATIONS AND PROCESSES FOR USING THE SAME TO IMPROVE STABILITY OF LIVING POLYMER CHAIN ENDS FMC CORPORATION (US) 2000-08-31 — — WO claimed
EP-1025085-A1 HETEROCYCLES USEFUL IN THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA AND INTERMEDIATES THEREOF Ortho-McNeil Pharmaceutical, Inc. (US) 2000-08-09 — — EP claimed
WO-2000015667-A1 CELLULOSE MICROFIBRILS WITH MODIFIED SURFACE, PREPARATION METHOD AND USE THEREOF RHODIA CHIMIE (FR) 2000-03-23 — — WO claimed
WO-1999019299-A1 HETEROCYCLES USEFUL IN THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA AND INTERMEDIATES THEREOF ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 1999-04-22 — — WO claimed
US-5621099-A CARDIOVASCULAR DISORDERS SUNTORY LIMITED (JP) 1997-04-15 — — US claimed
EP-0711773-A1 HYMENIALDISINE AND DERIVATIVE THEREOF, PROCESS FOR PRODUCING INTERMEDIATE FOR SYNTHESIZING THE SAME, AND SAID INTERMEDIATE SUNTORY LIMITED (JP) 1996-05-15 — — EP claimed
EP-0188247-B1 PROCESS FOR PREPARING AZETIDINONE INTERMEDIATES FARMITALIA CARLO ERBA S.r.l. (IT) 1991-04-03 — — EP claimed
US-4771134-A Ring-opening process for preparing azetidinone intermediates FARMITALIA CARLO ERBA S.P.A. (IT) 1988-09-13 — — US claimed
EP-0188247-A1 Process for preparing azetidinone intermediates FARMITALIA CARLO ERBA S.r.l. (IT) 1986-07-23 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009607-A1 METHOD FOR PREPARING DNA FRAGMENT HAVING STICKY END POLB, POLL, POLN MAPK1 4260/4885CA4 3286/4885NR1H2 4813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.