Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.41 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | CPN1 | P15169 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.35 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6632396 | 1.00 | EPHX1 (0.45) | EPHX1GABRA5GABRB2SLC6A1SLC6A12 | |
| Trifluoroacetic Acid SCHEMBL6626871 | 1.00 | EPHX1 (0.45) | EPHX1GABRA5GABRB2SLC6A1SLC6A12 | |
| SCHEMBL1802276 | 0.88 | EPHX1 (0.54) | EPHX1GABRA5GABRB2SLC6A1SLC6A12 | |
| Trifluoroacetic Acid SCHEMBL28044634 | 0.79 | GABRA5 (0.43) | EPHX1GABRA5GABRB2SLC6A1SLC6A12 | |
| Trifluoroacetic Acid SCHEMBL13254839 | 0.79 | GABRA5 (0.43) | EPHX1GABRA5GABRB2SLC6A1SLC6A12 | |
| Trifluoroacetic Acid SCHEMBL27969889 | 0.78 | EPHX2 (0.61) | CHRM1TSHR | |
| Trifluoroacetic Acid SCHEMBL6625874 | 0.78 | KEAP1 (0.38) | EPHX1ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL6631199 | 0.78 | KEAP1 (0.38) | EPHX1ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL844259 | 0.77 | GABRA5 (0.41) | EPHX1GABRA5GABRB2SLC6A1SLC6A12 | |
| Trifluoroacetic Acid SCHEMBL2997803 | 0.75 | GABRA5 (0.40) | EPHX1GABRA5GABRB2SLC6A1SLC6A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027332-B1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2004-05-26 | — | — | EP | disclosed |