Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6629542 | 0.86 | NR1H3 (0.58) | MGLLMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL9836388 | 0.80 | F2 (0.48) | MGLLMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL1471797 | 0.76 | MGLL (0.50) | MGLLMEN1KMT2APOLBACHE | |
| SCHEMBL1471737 | 0.76 | MGLL (0.50) | MGLLMEN1KMT2APOLBACHE | |
| SCHEMBL15354483 | 0.75 | ACHE (0.43) | MEN1KMT2AACHESMN1; SMN2NR1H3 | |
| SCHEMBL12341700 | 0.74 | ESR1 (0.63) | MGLLMEN1KMT2APOLBACHE | |
| SCHEMBL12572501 | 0.74 | ESR1 (0.62) | MEN1KMT2ASMN1; SMN2GAANR1H3 | |
| SCHEMBL16786672 | 0.73 | MEN1 (0.56) | MGLLMEN1KMT2APOLBACHE | |
| SCHEMBL10050140 | 0.73 | KMT2A (0.40) | MGLLMEN1KMT2AGAAAPP | |
| SCHEMBL29644729 | 0.72 | NR1H3 (0.69) | MGLLMEN1KMT2APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349860-B1 | SYNTHESES FOR PREPARING 1,4-DIKETOPYRROLO[3,4-C]PYRROLES | SUN CHEMICAL CORP (US) | 2004-08-18 | — | — | EP | disclosed |