SCHEMBL10050140

SCHEMBL10050140

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C3=C4C(=O)N(c5ccccc5)C(c5ccc(N(c6ccc(C)cc6)c6ccc(C)cc6)cc5)=C4C(=O)N3c3ccccc3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
GAA P10253 2/20 0.40
RAB9A P51151 1/20 0.40
APP P05067 1/20 0.40
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
HPGD P15428 1/20 0.38
BLM P54132 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ELANE P08246 3/20 0.37
F2 P00734 1/20 0.37
CTSG P08311 1/20 0.37
CMA1 P23946 1/20 0.37
CTRC Q99895 1/20 0.37
TLR9 Q9NR96 1/20 0.35
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.35
GABRA2 P47869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10050139 0.99 APP (0.42) KMT2AMEN1GAARAB9AAPP
SCHEMBL9836388 0.84 F2 (0.48) KMT2AMEN1GAARAB9AALDH1A1
SCHEMBL25849817 0.82 GAA (0.40) KMT2AMEN1GAARAB9AAPP
SCHEMBL25028129 0.79 APP (0.40) KMT2AMEN1APPALDH1A1KDM4E
SCHEMBL5068959 0.79 MGLL (0.46) KMT2AMEN1GAAALDH1A1TLR9
SCHEMBL15681729 0.78 PTGS2 (0.42) KMT2AMEN1APPALDH1A1KDM4E
SCHEMBL10050131 0.78 PTGS2 (0.42) KMT2AMEN1APPALDH1A1KDM4E
SCHEMBL23954215 0.76 HSP90AA1 (0.51) KMT2AMEN1GAARAB9AALDH1A1
SCHEMBL10050133 0.74 ALDH1A1 (0.42) KMT2AMEN1GAARAB9AAPP
SCHEMBL25028261 0.74 APP (0.33) KMT2AMEN1GAARAB9AAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956736-B2 Organic electroluminescent device and display apparatus SONY CORPORATION (JP) 2015-02-17 US disclosed
US-8956736-B2 Organic electroluminescent device and display apparatus SONY CORPORATION (JP) 2015-02-17 US disclosed
US-8569747-B2 Organic electroluminescence element and display device SONY CORPORATION (JP) 2013-10-29 US disclosed
US-8569747-B2 Organic electroluminescence element and display device SONY CORPORATION (JP) 2013-10-29 US disclosed
US-8541111-B2 Organic electroluminescent device and display apparatus SONY CORPORATION (JP) 2013-09-24 US disclosed
US-8541111-B2 Organic electroluminescent device and display apparatus SONY CORPORATION (JP) 2013-09-24 US disclosed
US-20120222794-A1 TRANSFER SUBSTRATE AND METHOD FOR FABRICATING ORGANIC ELECTROLUMINESCENT ELEMENT SONY CORPORATION (JP) 2012-09-06 US disclosed
US-8207088-B2 Transfer substrate and method for fabricating organic electroluminescent element SONY CORPORATION (JP) 2012-06-26 US disclosed
US-20110198577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE SONY CORPORATION (JP) 2011-08-18 US disclosed
US-20090045735-A1 TRANSFER SUBSTRATE AND METHOD FOR FABRICATING ORGANIC ELECTROLUMINESCENT ELEMENT SONY CORPORATION (JP) 2009-02-19 US disclosed
US-20090039769-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2009-02-12 US disclosed
US-20080292904-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2008-11-27 US disclosed
US-20080164809-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2008-07-10 US disclosed