Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202106 | 0.85 | RAB9A (0.59) | RAB9ALMNAGAAL3MBTL1NPC1 | |
| SCHEMBL5228689 | 0.78 | RAB9A (0.61) | RAB9ALMNAGAAL3MBTL1NPC1 | |
| SCHEMBL29447082 | 0.78 | RAB9A (0.61) | RAB9ALMNAGAAL3MBTL1NPC1 | |
| SCHEMBL3857668 | 0.78 | GLA (0.55) | RAB9ALMNAGAANPC1SMN1; SMN2 | |
| SCHEMBL14470498 | 0.76 | RAB9A (0.47) | RAB9ALMNAL3MBTL1NPC1SMN1; SMN2 | |
| SCHEMBL11116315 | 0.76 | L3MBTL1 (0.59) | RAB9ALMNAGAAL3MBTL1NPC1 | |
| SCHEMBL19756735 | 0.76 | RAB9A (0.49) | RAB9ALMNAGAAL3MBTL1NPC1 | |
| SCHEMBL7922085 | 0.76 | RAB9A (0.49) | RAB9ALMNAGAAL3MBTL1NPC1 | |
| SCHEMBL31731398 | 0.76 | RAB9A (0.49) | RAB9ALMNAGAAL3MBTL1NPC1 | |
| SCHEMBL701884 | 0.76 | TDP1 (0.54) | RAB9ALMNAGAAL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425283-A1 | NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF | Bayer HealthCare AG (DE) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003018589-A1 | NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2003-03-06 | — | — | WO | disclosed |