SCHEMBL701884

SCHEMBL701884

Cc1nc2cc(C(=O)O)ccc2o1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
GAA P10253 2/20 0.54
RAB9A P51151 7/20 0.52
NPC1 O15118 5/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
STAT1 P42224 1/20 0.52
TAS1R3 Q7RTX0 3/20 0.52
TAS1R1 Q7RTX1 3/20 0.52
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
KDM4E B2RXH2 2/20 0.50
MAPT P10636 2/20 0.50
CHRNA7 P36544 1/20 0.50
POLB P06746 1/20 0.50
LMNA P02545 1/20 0.48
HPGD P15428 2/20 0.46
ALDH1A1 P00352 1/20 0.46
EPHX2 P34913 1/20 0.46
MBOAT4 Q96T53 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30041235 1.00 TDP1 (0.54) TDP1L3MBTL1GAARAB9ANPC1
SCHEMBL2942587 0.87 L3MBTL1 (0.69) L3MBTL1GAARAB9ANPC1SMN1; SMN2
SCHEMBL29784106 0.86 TAS1R3 (0.57) TDP1GAARAB9ANPC1SMN1; SMN2
SCHEMBL703616 0.86 TAS1R3 (0.57) TDP1GAARAB9ANPC1SMN1; SMN2
SCHEMBL20482131 0.86 RAB9A (0.56) L3MBTL1GAARAB9ANPC1SMN1; SMN2
SCHEMBL13356595 0.85 RAB9A (0.51) L3MBTL1GAARAB9ANPC1SMN1; SMN2
SCHEMBL9181228 0.82 TAS1R3 (0.58) L3MBTL1GAARAB9ANPC1SMN1; SMN2
SCHEMBL27326882 0.82 TAS1R3 (0.58) TDP1L3MBTL1RAB9ANPC1SMN1; SMN2
SCHEMBL6790090 0.81 TDP1 (0.47) TDP1L3MBTL1GAARAB9ANPC1
SCHEMBL8051639 0.79 MEN1 (0.60) L3MBTL1GAARAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103923765-A Detergent Composition For Process Of Manufacturing Semiconductors And Displays COWON INNOTECH INC 2014-07-16 CN claimed
US-20230027198-A1 INHIBITORS OF ENL/AF9 YEATS THE ROCKEFELLER UNIVERSITY 2023-01-26 US disclosed
US-20230027198-A1 INHIBITORS OF ENL/AF9 YEATS THE ROCKEFELLER UNIVERSITY 2023-01-26 US disclosed
CN-115427035-A ENL/AF9YEATS inhibitors 洛克菲勒大学 2022-12-02 CN disclosed
EP-4076440-A1 INHIBITORS OF ENL/AF9 YEATS The Rockefeller University (US) 2022-10-26 EP disclosed
US-20220326230-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF FIRMENICH INCORPORATED (US) 2022-10-13 US disclosed
CN-114502158-A IRAK degradation agent and application thereof 凯麦拉医疗公司 2022-05-13 CN disclosed
CN-114269721-A Compounds for the treatment of respiratory diseases TMEM16A有限公司 2022-04-01 CN disclosed
US-11268952-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof FIRMENICH INCORPORATED (US) 2022-03-08 US disclosed
WO-2021127166-A1 INHIBITORS OF ENL/AF9 YEATS THE ROCKEFELLER UNIVERSITY (US) 2021-06-24 WO disclosed
WO-2003018589-A1 NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF BAYER HEALTHCARE AG (DE) 2003-03-06 WO disclosed
WO-2002100858-A2 QUINUCLIDINE-SUBSTITUTED HETEROAROMATIC COMPOUNDS AS LIGANDS AT NICOTINIC ACETYLCHOLINE RECEPTORS PHARMACIA & UPJOHN COMPANY (US) 2002-12-19 WO disclosed
US-6140036-A SILVER HALIDE PHOTOGRAPHIC FILMS AND CYANINE DYES EASTMAN KODAK COMPANY (US) 2000-10-31 US disclosed
EP-1033617-A1 Photographic material having improved color reproduction EASTMAN KODAK COMPANY (US) 2000-09-06 EP disclosed
EP-0323728-B1 FILTER DYES FOR PHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1993-10-13 EP disclosed
EP-0294461-B1 SOLID PARTICLE DISPERSION FILTER DYES FOR PHOTOGRAPHIC COMPOSITIONS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1991-10-23 EP disclosed
US-4900653-A SOLUBILITY; CYANINE DYES EASTMAN KODAK COMPANY (US) 1990-02-13 US disclosed
EP-0323728-A2 Filter dyes for photographic elements EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-07-12 EP disclosed
EP-0294461-A1 SOLID PARTICLE DISPERSION FILTER DYES FOR PHOTOGRAPHIC COMPOSITIONS. EASTMAN KODAK CO (US) 1988-12-14 EP disclosed
WO-1988004794-A1 SOLID PARTICLE DISPERSION FILTER DYES FOR PHOTOGRAPHIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1988-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230027198-A1 INHIBITORS OF ENL/AF9 YEATS MLLT3, YEATS2, MLLT1 TDP1 1399/4885L3MBTL1 410/4885GAA 3726/4885
US-20220326230-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF TAS1R2, TAS1R1, TAS2R30 TDP1 3974/4885L3MBTL1 4091/4885GAA 1180/4885
US-11268952-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof TAS2R40, TAS1R2, TAS1R1 TDP1 3965/4885L3MBTL1 3984/4885GAA 1043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.