Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPRG | P23470 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4836672 | 0.79 | GAA (0.37) | KMT2APOLBTDP1L3MBTL1MEN1 | |
| SCHEMBL6596838 | 0.78 | GPR35 (0.42) | KMT2AGPR35MAPTGSK3BPOLB | |
| SCHEMBL4078686 | 0.78 | GPR35 (0.42) | KMT2AGPR35GSK3BPOLBTDP1 | |
| SCHEMBL11325227 | 0.74 | GPR35 (0.39) | KMT2AGPR35GSK3BPOLBTDP1 | |
| SCHEMBL9405491 | 0.71 | MEN1 (0.44) | KMT2AL3MBTL1PTPRCMEN1TSHR | |
| SCHEMBL4885038 | 0.70 | GPR35 (0.36) | GPR35GSK3BPOLBTDP1L3MBTL1 | |
| SCHEMBL3636522 | 0.70 | L3MBTL1 (0.52) | KMT2AGPR35GSK3BPOLBTDP1 | |
| SCHEMBL787848 | 0.69 | GPR35 (0.47) | KMT2AGPR35POLBTDP1L3MBTL1 | |
| SCHEMBL27504482 | 0.67 | GPR35 (0.60) | KMT2AGPR35GSK3BPOLBTDP1 | |
| SCHEMBL18701570 | 0.67 | GPR35 (0.46) | KMT2AGPR35GSK3BPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485356-A1 | NON-PEPTIDE GnRH ANTAGONISTS | Ferring BV (NL) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003078398-A1 | NON-PEPTIDE GnRH ANTAGONISTS | FERRING BV (NL) | 2003-09-25 | — | — | WO | disclosed |