Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.38 |
| ▸ | ACACA | Q13085 | 9/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063420 | 0.92 | ACACB (0.38) | ACACBACACAPTPN2PTPN1CKS1B | |
| SCHEMBL6632355 | 0.88 | PTPN1 (0.40) | PTPN2PTPN1 | |
| SCHEMBL6628452 | 0.88 | PTPN1 (0.40) | PTPN2PTPN1 | |
| SCHEMBL6630253 | 0.84 | ACACB (0.36) | ACACBACACAPTPN2PTPN1 | |
| SCHEMBL6692395 | 0.81 | PTPN2 (0.38) | ACACBACACAPTPN2PTPN1 | |
| SCHEMBL6628528 | 0.79 | CTSK (0.37) | PTPN2PTPN1 | |
| SCHEMBL6063416 | 0.77 | ACACB (0.36) | ACACBACACAPTPN2PTPN1 | |
| SCHEMBL6628447 | 0.75 | MAPT (0.42) | PTPN2PTPN1 | |
| SCHEMBL6061710 | 0.75 | MAPT (0.42) | PTPN2PTPN1 | |
| SCHEMBL6206021 | 0.73 | CTSS (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397340-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002098850-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-12-12 | — | — | WO | disclosed |