Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.40 |
| ▸ | MERTK | Q12866 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | TOP2A | P11388 | 3/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6618211 | 0.86 | ADRA2A (0.44) | ALDH1A1NPY5RACACBACACA | |
| SCHEMBL3941128 | 0.85 | NPY5R (0.56) | NPY5RBCHEACHEAPPACACB | |
| SCHEMBL3941125 | 0.85 | NPY5R (0.56) | NPY5RBCHEACHEAPPACACB | |
| SCHEMBL6615961 | 0.78 | MCHR1 (0.45) | ALDH1A1NPY5RMEN1KMT2A | |
| SCHEMBL6930461 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL14266658 | 0.76 | MERTK (0.52) | ALDH1A1NPY5RMERTKBCHEACHE | |
| SCHEMBL14599452 | 0.74 | NPY5R (0.52) | ALDH1A1NPY5RBCHEACHEAPP | |
| SCHEMBL6615107 | 0.74 | SYK (0.47) | CFDNPY5RMERTKMEN1KMT2A | |
| SCHEMBL6603635 | 0.73 | ACACB (0.53) | NPY5RACACBACACA | |
| SCHEMBL4358020 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432693-A2 | MCH RECEPTOR ANTAGONISTS | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028641-A2 | MCH RECEPTOR ANTAGONISTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2003-04-10 | — | — | WO | disclosed |