Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22070528 | 0.84 | CYP4F2 (0.64) | CYP4F2CYP4A11POLBKMT2AALDH1A1 | |
| SCHEMBL22070545 | 0.82 | CYP4F2 (0.59) | CYP4F2CYP4A11POLBNPC1RAB9A | |
| SCHEMBL12660944 | 0.82 | CYP4F2 (0.64) | CYP4F2CYP4A11POLBNPC1RAB9A | |
| SCHEMBL9837746 | 0.81 | CYP4F2 (0.62) | CYP4F2CYP4A11DRD2DRD1DRD4 | |
| SCHEMBL1019684 | 0.81 | CYP4F2 (0.62) | CYP4F2CYP4A11DRD2DRD1DRD4 | |
| SCHEMBL9838425 | 0.81 | CYP4F2 (0.62) | CYP4F2CYP4A11DRD2DRD1DRD4 | |
| SCHEMBL29586758 | 0.81 | CYP4F2 (0.62) | CYP4F2CYP4A11DRD2DRD1DRD4 | |
| SCHEMBL20730230 | 0.80 | CYP4F2 (0.68) | CYP4F2CYP4A11POLBNPC1KMT2A | |
| SCHEMBL1020122 | 0.80 | CYP4F2 (0.61) | CYP4F2CYP4A11POLBNFKB1NFKB2 | |
| SCHEMBL1044067 | 0.80 | CYP4F2 (0.61) | CYP4F2CYP4A11POLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432696-A1 | CHROMAN DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | Wyeth (US) | 2004-06-30 | — | — | EP | disclosed |
| US-6706757-B2 | TREATING CENTRAL NERVOUS SYSTEM DISORDERS, CAUSED BY 5-HT6 RECEPTOR | WYETH | 2004-03-16 | — | — | US | disclosed |
| US-20030158175-A1 | Chroman derivatives as 5-hydroxytrytamine-6 ligands | WYETH | 2003-08-21 | — | — | US | disclosed |
| WO-2003029238-A1 | CHROMAN DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158175-A1 | Chroman derivatives as 5-hydroxytrytamine-6 ligands | HTR6, HTR1A, HTR1F | CYP4F2 496/4885CYP4A11 573/4885POLB 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.