Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.67 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PRNP | P04156 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601697 | 0.85 | ALDH1A1 (0.70) | CYSLTR2CYSLTR1MEN1KMT2APRNP | |
| SCHEMBL8355619 | 0.81 | LTB4R (0.56) | CYSLTR2CYSLTR1MEN1KMT2AMAPT | |
| SCHEMBL14021499 | 0.80 | CYSLTR1 (1.00) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL9243486 | 0.79 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1MEN1KMT2APRNP | |
| SCHEMBL9243481 | 0.79 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1MEN1KMT2APRNP | |
| Acetone SCHEMBL27714910 | 0.78 | KMT2A (0.49) | CYSLTR2CYSLTR1MEN1KMT2APRNP | |
| SCHEMBL9188602 | 0.78 | MAPT (0.50) | CYSLTR2CYSLTR1MEN1KMT2AALDH1A1 | |
| SCHEMBL11184442 | 0.78 | LTB4R (0.67) | TOP2APDE5A | |
| SCHEMBL4273391 | 0.78 | MAPT (0.59) | CYSLTR2CYSLTR1MEN1KMT2AKDM4E | |
| SCHEMBL10544504 | 0.78 | CYSLTR1 (1.00) | CYSLTR2CYSLTR1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412349-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | Schering Aktiengesellschaft (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002098856-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-12 | — | — | WO | disclosed |