Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SYK | P43405 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.51 |
| ▸ | RELA | Q04206 | 3/20 | 0.51 |
| ▸ | FOS | P01100 | 2/20 | 0.51 |
| ▸ | JUN | P05412 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6632274 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL16274792 | 0.83 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL445955 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL6631142 | 0.82 | ALDH1A1 (0.64) | ALDH1A1MAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL6623774 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL6633102 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL6631911 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL1313596 | 0.80 | SYK (0.79) | ALDH1A1MAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL25829315 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL6631793 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTSMN1; SMN2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430898-A1 | RECEPTOR ANTAGONIST | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-06-23 | — | — | EP | disclosed |
| US-20040110826-A1 | Receptor Antagonists | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110826-A1 | Receptor Antagonists | ADRA2C, OPRL1, ADRB1 | ALDH1A1 1430/4885MAPT 2392/4885SMN1; SMN2 2635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.