Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20599671 | 0.77 | HIF1A (0.33) | — | |
| SCHEMBL20599721 | 0.73 | SMN1; SMN2 (0.39) | MPO | |
| SCHEMBL5647904 | 0.71 | HPGD (0.33) | — | |
| SCHEMBL5650940 | 0.71 | TP53 (0.42) | — | |
| SCHEMBL30137420 | 0.64 | PDK2 (0.37) | — | |
| SCHEMBL28768902 | 0.64 | LMNA (0.36) | — | |
| SCHEMBL12492678 | 0.63 | — | — | |
| SCHEMBL31243248 | 0.62 | — | — | |
| SCHEMBL440250 | 0.61 | — | — | |
| SCHEMBL3907527 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458375-A2 | COMPOSITIONS FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051842-A2 | COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |