Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627833 | 0.83 | ADORA2A (0.66) | ADORA3ADORA2AADORA1ADORA2BKMT2A | |
| SCHEMBL6631103 | 0.79 | ADORA3 (0.63) | ADORA3ADORA2AADORA1ADORA2BALDH1A1 | |
| SCHEMBL6631069 | 0.76 | ADORA3 (0.68) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL6633210 | 0.76 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL6632640 | 0.75 | ADORA2A (0.50) | ADORA3ADORA2AADORA1ADORA2BMAPT | |
| SCHEMBL10712100 | 0.72 | ADORA3 (0.61) | ADORA3ADORA2AADORA1ADORA2BALDH1A1 | |
| SCHEMBL31657838 | 0.72 | ADORA3 (0.61) | ADORA3ADORA2AADORA1ADORA2BALDH1A1 | |
| SCHEMBL31657841 | 0.72 | ADORA3 (0.61) | ADORA3ADORA2AADORA1ADORA2BALDH1A1 | |
| SCHEMBL29335112 | 0.72 | HSD17B10 (0.65) | ADORA3ADORA2AADORA1ADORA2BALDH1A1 | |
| SCHEMBL6623318 | 0.71 | ADORA3 (0.76) | ADORA3ADORA2AADORA1ADORA2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430898-A1 | RECEPTOR ANTAGONIST | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-06-23 | — | — | EP | disclosed |
| US-20040110826-A1 | Receptor Antagonists | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110826-A1 | Receptor Antagonists | ADRA2C, OPRL1, ADRB1 | ADORA3 85/4885ADORA2A 89/4885ADORA1 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.