Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 12/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205280 | 0.83 | GSK3B (0.80) | GSK3BPTPN1 | |
| SCHEMBL9237039 | 0.82 | GSK3B (0.64) | GSK3BPTPN1CES2CES1 | |
| SCHEMBL6816324 | 0.82 | GSK3B (0.64) | GSK3BPTPN1CES2CES1 | |
| SCHEMBL1365349 | 0.80 | GSK3B (0.61) | GSK3BPTPN1CES2CES1 | |
| SCHEMBL7328068 | 0.79 | GSK3B (0.55) | GSK3BPTPN1CES2CES1 | |
| SCHEMBL306422 | 0.78 | MAPT (0.53) | IDO1 | |
| SCHEMBL2776629 | 0.78 | GSK3B (0.63) | GSK3BPTPN1 | |
| SCHEMBL16057598 | 0.78 | PTPN1 (0.63) | GSK3BPTPN1CES2CES1 | |
| SCHEMBL14227546 | 0.78 | GSK3B (0.59) | GSK3BPTPN1CES2CES1 | |
| SCHEMBL392969 | 0.77 | GSK3B (0.59) | GSK3BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170144968-A1 | PROCESS FOR PREPARATION OF PYRROLES HAVING HYPOLIPIDEMIC HYPOCHOLESTEREMIC ACTIVITIES | ZYDUS LIFESCIENCES LIMITED (IN) | 2017-05-25 | — | — | US | disclosed |
| US-20160194280-A1 | IMPROVED PROCESS FOR THE PREPARATION OF PYRROLE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2016-07-07 | — | — | US | disclosed |
| US-20160107989-A1 | A PROCESS FOR PREPARATION OF PYRROLES HAVING HYPOLIPIDEMIC HYPOCHOLESTEREMIC ACTIVITIES | CADILA HEALTHCARE LIMITED (IN) | 2016-04-21 | — | — | US | disclosed |
| EP-1394162-A1 | Intermediates of azole antifungal agents and processes for the preparation thereof | Eisai Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-1394142-A1 | Carboxylic acid intermediates of antifungal agents and processes for the preparation thereof | Eisai Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-1231210-A2 | Azole antifungal agents, processes for the preparation thereof, and intermediates | Eisai Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-5792781-A | EFFECTIVE AGAINST DERMATOMYCOSIS/VISCEROMYCOSIS CAUSED BY FUNGI, I.E., CANDIDA ALBICANS | EISAI CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| US-5789429-A | FUNGICIDE | EISAI CO., LTD. (JP) | 1998-08-04 | — | — | US | disclosed |
| US-5648372-A | TRIAZOLES | EISAI CO., LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0667346-A2 | Azole antifungal agents, process for the preparation there of and intermediates | Eisai Co., Ltd. (JP) | 1995-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194280-A1 | IMPROVED PROCESS FOR THE PREPARATION OF PYRROLE DERIVATIVES | HPD, HMGCR, CYP51A1 | GSK3B 3068/4885PTPN1 501/4885CES2 919/4885 |
| US-20160107989-A1 | A PROCESS FOR PREPARATION OF PYRROLES HAVING HYPOLIPIDEMIC HYPOCHOLESTEREMIC ACTIVITIES | CYP51A1, DHCR7, LIPA | GSK3B 2947/4885PTPN1 1289/4885CES2 1958/4885 |
| US-20170144968-A1 | PROCESS FOR PREPARATION OF PYRROLES HAVING HYPOLIPIDEMIC HYPOCHOLESTEREMIC ACTIVITIES | CYP51A1, LIPA, DHCR7 | GSK3B 2585/4885PTPN1 1466/4885CES2 2040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.