Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 13/20 | 0.70 |
| ▸ | CYP1A1 | P04798 | 12/20 | 0.70 |
| ▸ | CYP1B1 | Q16678 | 12/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.58 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.58 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.58 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.58 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.58 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631188 | 0.83 | CYP1A1 (0.61) | CYP1A2CYP1A1CYP1B1ALDH1A1NFE2L2 | |
| SCHEMBL25706432 | 0.83 | CYP1A2 (1.00) | CYP1A2CYP1A1CYP1B1ALDH1A1NFE2L2 | |
| SCHEMBL145083 | 0.83 | CYP1A2 (0.76) | CYP1A2CYP1A1CYP1B1ALDH1A1NFE2L2 | |
| SCHEMBL1547597 | 0.81 | CYP1A2 (0.73) | CYP1A2CYP1A1CYP1B1ALDH1A1NFE2L2 | |
| SCHEMBL27567539 | 0.80 | CYP1A2 (0.66) | CYP1A2CYP1A1CYP1B1ALDH1A1NFE2L2 | |
| SCHEMBL96291 | 0.79 | ALDH1A1 (1.00) | CYP1A2CYP1A1CYP1B1ALDH1A1NFE2L2 | |
| SCHEMBL9545111 | 0.79 | CYP1A2 (0.70) | CYP1A2CYP1A1CYP1B1ALDH1A1NFE2L2 | |
| SCHEMBL11108516 | 0.79 | CYP1A2 (0.70) | CYP1A2CYP1A1CYP1B1ALDH1A1NFE2L2 | |
| SCHEMBL30411244 | 0.79 | CYP1A2 (0.70) | CYP1A2CYP1A1CYP1B1ALDH1A1NFE2L2 | |
| SCHEMBL7003172 | 0.79 | CYP1A2 (0.70) | CYP1A2CYP1A1CYP1B1ALDH1A1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471178-A | Process for preparing radiolabeled peptides | SIEMENS AG | 2012-05-23 | — | — | CN | disclosed |
| CN-1500086-A | Aminopiperidine derivatives | 霍夫曼-拉罗奇有限公司 | 2004-05-26 | — | — | CN | disclosed |
| EP-1417202-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-12 | — | — | EP | disclosed |
| US-20030069276-A1 | Amino piperidine derivatives | F.HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | US | disclosed |
| WO-2002079186-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2002-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069276-A1 | Amino piperidine derivatives | CCR5, CCR2, CXCR4 | CYP1A2 1693/4885CYP1A1 1994/4885CYP1B1 2146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.