Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631816 | 0.87 | ADORA3 (0.58) | ADORA3ADORA2AADORA1ADORA2BSMN1; SMN2 | |
| SCHEMBL6633307 | 0.86 | ADORA3 (0.51) | ADORA3ADORA2AADORA1ADORA2BSMN1; SMN2 | |
| SCHEMBL6630937 | 0.85 | ADORA3 (0.51) | ADORA3ADORA2AADORA1ADORA2BSMN1; SMN2 | |
| SCHEMBL6632120 | 0.84 | ADORA3 (0.55) | ADORA3ADORA2AADORA1ADORA2BSMN1; SMN2 | |
| SCHEMBL6633062 | 0.83 | ADORA3 (0.69) | ADORA3ADORA2AADORA1ADORA2BSMN1; SMN2 | |
| SCHEMBL6632798 | 0.83 | ADORA3 (0.54) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL6632142 | 0.82 | ADORA3 (0.53) | ADORA3ADORA2AADORA1ADORA2BSMN1; SMN2 | |
| SCHEMBL6631809 | 0.81 | ADORA3 (0.46) | ADORA3ADORA2AADORA1ADORA2BSMN1; SMN2 | |
| SCHEMBL6633336 | 0.80 | ADORA3 (0.53) | ADORA3ADORA2AADORA1ADORA2BTHRB | |
| SCHEMBL6623318 | 0.80 | ADORA3 (0.76) | ADORA3ADORA2AADORA1ADORA2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430898-A1 | RECEPTOR ANTAGONIST | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-06-23 | — | — | EP | disclosed |
| US-20040110826-A1 | Receptor Antagonists | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110826-A1 | Receptor Antagonists | ADRA2C, OPRL1, ADRB1 | ADORA3 85/4885ADORA2A 89/4885ADORA1 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.