Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634874 | 0.94 | P2RX7 (0.68) | P2RX7KDM4EMAPTEPHX1ALOX5 | |
| SCHEMBL8208778 | 0.94 | P2RX7 (0.68) | P2RX7KDM4EMAPTEPHX1ALOX5 | |
| SCHEMBL23048462 | 0.85 | CYP1A2 (0.67) | KDM4EMAPTEPHX1GAACYP1A2 | |
| SCHEMBL31091435 | 0.81 | EP300 (0.66) | KDM4EMAPTEPHX1GLAGAA | |
| SCHEMBL5923508 | 0.80 | P2RX7 (0.88) | P2RX7KDM4EMAPTALOX5GAA | |
| SCHEMBL28931497 | 0.79 | ALDH1A1 (0.66) | KDM4EEPHX1GAACYP1A2CYP2C19 | |
| SCHEMBL27812836 | 0.79 | P2RX7 (0.62) | P2RX7ALOX5GAAPOLBCETP | |
| SCHEMBL6636560 | 0.78 | METAP2 (0.54) | P2RX7KDM4EMAPTEPHX1GAA | |
| SCHEMBL12456328 | 0.76 | CYP2C19 (0.72) | KDM4EMAPTEPHX1GAARAB9A | |
| SCHEMBL12608238 | 0.76 | CYP2C19 (0.72) | KDM4EMAPTEPHX1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |