Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4595449 | 0.90 | PRSS1 (0.43) | GAALMNAALDH1A1AGTR1HTT | |
| SCHEMBL4595499 | 0.80 | ELANE (0.49) | GAALMNAKMT2AMEN1HSD17B10 | |
| SCHEMBL11822391 | 0.79 | LMNA (0.50) | LMNAALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL6632193 | 0.78 | RIPK1 (0.50) | GAALMNAALDH1A1AGTR1HTT | |
| SCHEMBL4593922 | 0.78 | ELANE (0.45) | LMNAHSD17B10CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11577532 | 0.77 | GAA (0.56) | GAALMNAALDH1A1AGTR1HTT | |
| SCHEMBL11577587 | 0.77 | GAA (0.47) | GAALMNAALDH1A1AGTR1HTT | |
| SCHEMBL11729702 | 0.76 | GAA (0.47) | GAALMNAALDH1A1AGTR1HTT | |
| SCHEMBL31266976 | 0.75 | L3MBTL1 (0.61) | GAALMNAALDH1A1AGTR1HTT | |
| SCHEMBL7196524 | 0.75 | GAA (0.59) | GAALMNAALDH1A1AGTR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417209-A1 | HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS | Crompton Corporation (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003014130-A1 | HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS | CROMPTON CORPORATION (US) | 2003-02-20 | — | — | WO | disclosed |