Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PNMT | P11086 | 13/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615168 | 1.00 | MEN1 (0.56) | MEN1KMT2APNMTADRA2AADRA2B | |
| SCHEMBL6618341 | 0.92 | MEN1 (0.51) | MEN1KMT2APNMTADRA2AADRA2B | |
| SCHEMBL6618053 | 0.92 | MEN1 (0.68) | MEN1KMT2APNMTADRA2AADRA2B | |
| SCHEMBL6616133 | 0.92 | MEN1 (0.68) | MEN1KMT2APNMTADRA2AADRA2B | |
| SCHEMBL6614938 | 0.83 | MEN1 (0.51) | MEN1KMT2APNMTADRA2AADRA2B | |
| SCHEMBL6640481 | 0.83 | MEN1 (0.51) | MEN1KMT2APNMTADRA2AADRA2B | |
| SCHEMBL6640477 | 0.83 | MEN1 (0.51) | MEN1KMT2APNMTADRA2AADRA2B | |
| SCHEMBL6615300 | 0.79 | MEN1 (0.46) | MEN1KMT2APNMTADRA2AADRA2B | |
| SCHEMBL6615411 | 0.79 | PNMT (0.45) | MEN1KMT2APNMTADRA2AADRA2B | |
| SCHEMBL6616447 | 0.79 | MEN1 (0.51) | MEN1KMT2APNMTADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481975-A1 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| US-6455523-B1 | ADMINISTERING 1,4-BENZODIAZEPINE DERIVATIVE AS ANTITUMOR OR ANTICARCINOGENIC AGENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-24 | — | — | US | disclosed |
| US-6011029-A | BENZODIAZEPINE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-01-04 | — | — | US | disclosed |