Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.67 |
| ▸ | METAP2 | P50579 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16866256 | 0.84 | GAA (0.68) | HDAC3HDAC1HDAC2RAB9AKMT2A | |
| SCHEMBL6638062 | 0.83 | HDAC3 (0.77) | HDAC3HDAC1HDAC2RAB9ADEGS1 | |
| SCHEMBL5592711 | 0.80 | RAB9A (0.58) | HDAC3HDAC1HDAC2RAB9AKMT2A | |
| SCHEMBL17141739 | 0.80 | HDAC3 (1.00) | HDAC3HDAC1HDAC2KMT2AHDAC8 | |
| SCHEMBL6638846 | 0.78 | HDAC3 (1.00) | HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL13569035 | 0.77 | HDAC3 (0.60) | HDAC3HDAC1HDAC2RAB9AKMT2A | |
| SCHEMBL27578181 | 0.77 | HDAC3 (0.64) | HDAC3HDAC1HDAC2RAB9ADEGS1 | |
| SCHEMBL7836520 | 0.77 | SMN1; SMN2 (0.61) | RAB9AKMT2AHDAC8MEN1NPC1 | |
| SCHEMBL27641548 | 0.77 | HDAC3 (0.63) | HDAC3HDAC1HDAC2RAB9ADEGS1 | |
| SCHEMBL13753280 | 0.76 | MLYCD (0.55) | HDAC3HDAC1HDAC2RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |