SCHEMBL6633628

SCHEMBL6633628

Cc1nc(Cl)sc1S(=O)(=O)NC1(F)CC1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 1/20 0.34
LGALS3 P17931 1/20 0.34
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6621823 0.75 ALDH1A1 (0.40) LGALS8LGALS3ALDH1A1HPGDTSHR
SCHEMBL7252974 0.72 CA12 (0.43) LGALS8LGALS3ALDH1A1HPGDTSHR
SCHEMBL3569943 0.71 ALDH1A1 (0.37) LGALS8LGALS3ALDH1A1HPGDTSHR
SCHEMBL1177539 0.69 ALDH1A1 (0.44) LGALS8LGALS3ALDH1A1HPGDTSHR
SCHEMBL1177587 0.69 ALDH1A1 (0.44) LGALS8LGALS3ALDH1A1HPGDTSHR
SCHEMBL2823087 0.68 ALDH1A1 (0.47) LGALS8LGALS3ALDH1A1HPGDTSHR
Hydrochloric Acid SCHEMBL28079046 0.66 ALDH1A1 (0.46) LGALS8LGALS3ALDH1A1HPGDTSHR
SCHEMBL2977409 0.66 HSD17B10 (0.38) ALDH1A1HPGD
SCHEMBL2977405 0.65 CA12 (0.39) LGALS8LGALS3ALDH1A1HPGDTSHR
SCHEMBL2626882 0.65 TSHR (0.40) LGALS8LGALS3ALDH1A1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040235916-A1 Thiazolyl amides and their use as antiviral drugs SCHOHE-LOOP RUDOLF (DE) 2004-11-25 US disclosed
EP-1401436-A1 THIAZOLYL AMIDES AND THEIR USE AS ANTIVIRAL DRUGS Bayer HealthCare AG (DE) 2004-03-31 EP disclosed
WO-2003000260-A1 THIAZOLYL AMIDES AND THEIR USE AS ANTIVIRAL DRUGS BAYER HEALTHCARE AG (DE) 2003-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040235916-A1 Thiazolyl amides and their use as antiviral drugs EIF2AK2, MAVS, ZC3HAV1 LGALS8 2221/4885LGALS3 3161/4885ALDH1A1 952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.