Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | GRK5 | P34947 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177539 | 0.83 | ALDH1A1 (0.44) | ALDH1A1HPGDTSHRLGALS8LGALS3 | |
| SCHEMBL2823087 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HPGDTSHRLGALS8LGALS3 | |
| SCHEMBL50966 | 0.80 | NPY5R (0.32) | — | |
| Hydrochloric Acid SCHEMBL28079046 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDTSHRLGALS8LGALS3 | |
| SCHEMBL2626882 | 0.78 | TSHR (0.40) | ALDH1A1HPGDTSHRLGALS8LGALS3 | |
| SCHEMBL6621823 | 0.78 | ALDH1A1 (0.40) | ALDH1A1HPGDTSHRLGALS8LGALS3 | |
| SCHEMBL9666619 | 0.77 | HTR6 (0.32) | — | |
| SCHEMBL761873 | 0.77 | NOS1 (0.46) | ALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL23497255 | 0.74 | KMT2A (0.44) | ALDH1A1TSHRKMT2AL3MBTL1CDK7 | |
| SCHEMBL6572565 | 0.74 | GRM4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109054648-A | Serosity combination for chemically mechanical polishing | LTCAM有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-104419326-A | Slurry composition for chemical mechanical polishing | COWON INNOTECH INC | 2015-03-18 | — | — | CN | claimed |
| WO-2025049275-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| CN-119462555-A | Sulfonamide compound and application thereof | 上海科技大学 | 2025-02-18 | — | — | CN | disclosed |
| WO-2025031360-A1 | SULFONAMIDE COMPOUND AND USE THEREOF | 上海科技大学 | 2025-02-13 | — | — | WO | disclosed |
| US-20230151016-A1 | PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2023-05-18 | — | — | US | disclosed |
| US-20230151016-A1 | PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2023-05-18 | — | — | US | disclosed |
| US-20230151016-A1 | PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2023-05-18 | — | — | US | disclosed |
| US-11566030-B2 | Substituted 2,6-dihydropyrrolo[3,4-c]pyrazoles as pyruvate kinase activators | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2023-01-31 | — | — | US | disclosed |
| US-11566030-B2 | Substituted 2,6-dihydropyrrolo[3,4-c]pyrazoles as pyruvate kinase activators | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2023-01-31 | — | — | US | disclosed |
| US-20220267337-A1 | PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2022-08-25 | — | — | US | disclosed |
| WO-2003000260-A1 | THIAZOLYL AMIDES AND THEIR USE AS ANTIVIRAL DRUGS | BAYER HEALTHCARE AG (DE) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000259-A1 | TOPICAL APPLICATION OF THIAZOLYL AMIDES | BAYER HEALTHCARE AG (DE) | 2003-01-03 | — | — | WO | disclosed |
| US-6500817-B1 | HERPES SIMPLEX | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |
| EP-1244641-A1 | THIAZOLYL AMIDE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2002-10-02 | — | — | EP | disclosed |
| US-20020119995-A1 | Inverse thiazolylamide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-29 | — | — | US | disclosed |
| WO-2002012211-A1 | INVERSE THIAZOLYL AMIDE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-02-14 | — | — | WO | disclosed |
| EP-1161423-A1 | THIAZOLYL UREA DERIVATIVES AND THEIR UTILIZATION AS ANTIVIRAL AGENTS | Bayer Aktiengesellschaft (DE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2001047904-A1 | THIAZOLYL AMIDE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-05 | — | — | WO | disclosed |
| WO-2000053591-A1 | THIAZOLYL UREA DERIVATIVES AND THEIR UTILIZATION AS ANTIVIRAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566030-B2 | Substituted 2,6-dihydropyrrolo[3,4-c]pyrazoles as pyruvate kinase activators | PDK1, PDK2, PDK3 | ALDH1A1 1703/4885HPGD 1279/4885TSHR 2316/4885 |
| US-20220267337-A1 | PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS | PDK1, PDK2, PKM | ALDH1A1 1784/4885HPGD 1078/4885TSHR 2499/4885 |
| US-20230151016-A1 | PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS | PDK1, PDK2, PKM | ALDH1A1 1784/4885HPGD 1078/4885TSHR 2499/4885 |
| US-20020119995-A1 | Inverse thiazolylamide derivatives | MAVS, DPP4, EIF2AK2 | ALDH1A1 3229/4885HPGD 2702/4885TSHR 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.