Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 3/20 | 0.57 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.57 |
| ▸ | MAP4K1 | Q92918 | 16/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636281 | 0.88 | MAP4K1 (0.55) | MAP4K1 | |
| SCHEMBL31375795 | 0.77 | PRKCD (0.56) | PRKCHPRKCEPRKCQPRKCDROCK2 | |
| SCHEMBL11374306 | 0.77 | PRKCD (0.56) | PRKCHPRKCEPRKCQPRKCDROCK2 | |
| SCHEMBL27797340 | 0.77 | PRKCH (0.53) | PRKCHPRKCEPRKCQPRKCDMAP4K1 | |
| SCHEMBL11365647 | 0.76 | LMNA (0.44) | — | |
| SCHEMBL11374540 | 0.76 | HSP90AA1 (0.49) | PRKCHPRKCEPRKCQPRKCDMAP4K1 | |
| SCHEMBL11385106 | 0.76 | LMNA (0.46) | — | |
| SCHEMBL11374210 | 0.76 | HSP90AA1 (0.51) | MAP4K1 | |
| SCHEMBL11241124 | 0.76 | ROCK2 (0.43) | PRKCHPRKCEPRKCQPRKCDMAP4K1 | |
| SCHEMBL11377648 | 0.75 | MAP4K1 (0.60) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912571-B1 | NAPHTHYRIDINES WHICH AFFECT IL-4 AND G-CSF | SCHERING CORP (US) | 2004-08-04 | — | — | EP | disclosed |
| US-5939431-A | Naphthyridines which affect IL-4 and G-CSF | SCHERING CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| EP-0912571-A2 | NAPHTHYRIDINES WHICH AFFECT IL-4 AND G-CSF | SCHERING CORPORATION (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997048368-A2 | NAPHTHYRIDINES WHICH AFFECT IL-4 AND G-CSF | SCHERING CORPORATION (US) | 1997-12-24 | — | — | WO | disclosed |
| US-4293220-A | Application of inductively coupled plasma emission spectrometry to the elemental analysis of organic compounds and to the determination of the empirical formulas for these and other compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4260759-A | CONDENSATION OF NITRILES | SCHERING-CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
| US-4115395-A | FUNGICIDES, BACTERICIDES | SCHERING CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
| US-4107166-A | ANTIFUNGAL, ANTIBACTERIAL | SCHERING CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4017500-A | FUNGICIDES, BACTERICIDES | SCHERING CORPORATION (US) | 1977-04-12 | — | — | US | disclosed |