Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148346 | 0.82 | AOC3 (0.38) | HPGDSMN1; SMN2AOC3KMT2AMEN1 | |
| SCHEMBL3818616 | 0.78 | MEN1 (0.45) | HPGDSMN1; SMN2AOC3KMT2AMEN1 | |
| SCHEMBL27532126 | 0.76 | NUDT1 (0.47) | HPGDSMN1; SMN2AOC3MAPTALDH1A1 | |
| SCHEMBL3166513 | 0.71 | KMT2A (0.50) | SMN1; SMN2KMT2AMEN1TSHRMAPT | |
| SCHEMBL11790398 | 0.68 | AOC3 (0.37) | HPGDSMN1; SMN2AOC3KMT2AMEN1 | |
| SCHEMBL12614887 | 0.67 | NQO1 (0.48) | KMT2AMEN1POLBTSHRMAPT | |
| SCHEMBL29253548 | 0.67 | HPGD (0.41) | HPGDSMN1; SMN2AOC3KMT2AMEN1 | |
| SCHEMBL23937859 | 0.67 | AOC3 (0.36) | HPGDSMN1; SMN2AOC3KMT2AMEN1 | |
| SCHEMBL20116948 | 0.67 | KMT2A (0.39) | HPGDSMN1; SMN2AOC3KMT2APOLB | |
| SCHEMBL27035942 | 0.65 | NUDT1 (0.49) | KMT2AMEN1MAPTNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456201-A1 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053957-A1 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (US) | 2003-07-03 | — | — | WO | disclosed |