Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631787 | 0.83 | KMT2A (0.42) | RAB9ANPC1F2PLAUKLKB1 | |
| SCHEMBL6633229 | 0.83 | SMN1; SMN2 (0.42) | RAB9ANPC1PLAUELANESMN1; SMN2 | |
| SCHEMBL6629379 | 0.77 | NPC1 (0.46) | RAB9ANPC1F2PLAUKLKB1 | |
| SCHEMBL6636297 | 0.76 | MEN1 (0.43) | RAB9ANPC1PLAUELANESMN1; SMN2 | |
| SCHEMBL27406517 | 0.75 | SMN1; SMN2 (0.42) | RAB9ANPC1SMN1; SMN2GAAKMT2A | |
| SCHEMBL6632002 | 0.74 | SMN1; SMN2 (0.53) | RAB9ANPC1SMN1; SMN2GAAKMT2A | |
| SCHEMBL27874680 | 0.73 | SMN1; SMN2 (0.48) | RAB9ANPC1SMN1; SMN2GAAKMT2A | |
| SCHEMBL6635974 | 0.73 | MAPT (0.43) | RAB9ANPC1SMN1; SMN2GAAKMT2A | |
| SCHEMBL6634395 | 0.71 | SMN1; SMN2 (0.44) | RAB9ANPC1SMN1; SMN2GAAKMT2A | |
| SCHEMBL6630652 | 0.70 | GAA (0.45) | RAB9ANPC1SMN1; SMN2GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458375-A2 | COMPOSITIONS FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051842-A2 | COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |