Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635177 | 0.94 | USP2 (0.32) | ALDH1A1PTGESMMP2MMP9MMP14 | |
| SCHEMBL6631926 | 0.93 | USP2 (0.33) | ALDH1A1MMP2MMP9MMP14MAPT | |
| SCHEMBL6633485 | 0.92 | — | — | |
| SCHEMBL6634428 | 0.91 | ALDH1A1 (0.33) | ALDH1A1PTGESKDM4EHSP90AA1MAPT | |
| SCHEMBL6633703 | 0.90 | ALDH1A1 (0.37) | ALDH1A1PTGESKDM4EHSP90AA1MAPT | |
| SCHEMBL6633579 | 0.90 | HSD11B1 (0.32) | — | |
| SCHEMBL6634581 | 0.89 | — | — | |
| SCHEMBL6633406 | 0.89 | — | — | |
| SCHEMBL6634608 | 0.89 | KMT2A (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6637448 | 0.88 | NR1H2 (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-B1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |