Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633780 | 0.93 | NCEH1 (0.32) | RAB9AGAANPY2R | |
| SCHEMBL6633768 | 0.93 | TDP1 (0.35) | ALDH1A1KDM4EMAPTRAB9AGAA | |
| SCHEMBL6634428 | 0.91 | ALDH1A1 (0.33) | ALDH1A1PTGESKDM4EHSP90AA1MAPT | |
| SCHEMBL6635534 | 0.90 | ALDH1A1 (0.33) | ALDH1A1PTGESKDM4EHSP90AA1MAPT | |
| SCHEMBL6635393 | 0.89 | HSD11B1 (0.32) | — | |
| SCHEMBL6632994 | 0.86 | HTR1A (0.31) | — | |
| SCHEMBL6633399 | 0.86 | KEAP1 (0.36) | ALDH1A1MAPTKMT2AGAAKEAP1 | |
| SCHEMBL6637256 | 0.86 | NPY2R (0.38) | ALDH1A1MAPTNPY2RKEAP1NFE2L2 | |
| SCHEMBL6632832 | 0.84 | NCEH1 (0.31) | — | |
| SCHEMBL6632840 | 0.84 | TDP1 (0.32) | ALDH1A1KDM4EMAPTRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-B1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |