Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | S100A4 | P26447 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635718 | 0.91 | MEN1 (0.50) | MEN1KMT2AUSP2S100A4KDM4E | |
| SCHEMBL29506042 | 0.80 | KDM4E (0.61) | MEN1KMT2AUSP2S100A4KDM4E | |
| SCHEMBL165220 | 0.80 | KDM4E (0.61) | MEN1KMT2AUSP2S100A4KDM4E | |
| SCHEMBL18499925 | 0.77 | MTNR1B (0.47) | MEN1KMT2AUSP2S100A4MTNR1A | |
| SCHEMBL6633781 | 0.76 | MTNR1A (0.43) | MTNR1AMTNR1B | |
| SCHEMBL30067546 | 0.76 | ALDH1A1 (0.44) | MEN1KMT2AUSP2S100A4KDM4E | |
| SCHEMBL30067411 | 0.76 | ALDH1A1 (0.44) | MEN1KMT2AUSP2S100A4KDM4E | |
| SCHEMBL16230011 | 0.75 | ALDH1A1 (0.61) | MEN1KMT2AUSP2S100A4KDM4E | |
| SCHEMBL6634264 | 0.75 | MTNR1A (0.39) | MTNR1AMTNR1B | |
| SCHEMBL6634288 | 0.74 | MTNR1A (0.44) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047664-B1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |