Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6641028 | 0.90 | PPOX (0.40) | KDM4EKMT2AALDH1A1POLBGAA | |
| SCHEMBL6637267 | 0.83 | LMNA (0.38) | LMNAKDM4EKMT2AALDH1A1SYK | |
| SCHEMBL6640252 | 0.82 | MEN1 (0.38) | LMNAKDM4EKMT2AALDH1A1POLB | |
| SCHEMBL6665164 | 0.81 | LMNA (0.41) | LMNAKDM4EKMT2AALDH1A1POLB | |
| SCHEMBL8603307 | 0.79 | LMNA (0.65) | LMNAKDM4EALDH1A1GAATSHR | |
| SCHEMBL6639776 | 0.78 | PPOX (0.40) | LMNAKDM4EKMT2AALDH1A1POLB | |
| SCHEMBL13841333 | 0.78 | LMNA (0.50) | LMNAKDM4EKMT2AALDH1A1GAA | |
| SCHEMBL3250748 | 0.78 | MAPK8 (0.43) | LMNA | |
| SCHEMBL6637876 | 0.76 | BCAT1 (0.46) | — | |
| SCHEMBL6641762 | 0.76 | LMNA (0.32) | LMNAMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122244-B1 | Uracil compounds and their use | SUMITOMO CHEMICAL CO (JP) | 2004-09-29 | — | — | EP | claimed |
| US-6537948-B1 | Have a wide range of herbicidal spectrum, and causes no phytotoxicity on crops | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-25 | — | — | US | claimed |
| EP-1122244-A1 | Uracil compounds and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-08 | — | — | EP | claimed |
| EP-1122244-B1 | Uracil compounds and their use | SUMITOMO CHEMICAL CO (JP) | 2004-09-29 | — | — | EP | disclosed |