Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633740 | 0.79 | MTNR1A (0.65) | MTNR1BMTNR1A | |
| SCHEMBL6635819 | 0.76 | MTNR1B (0.54) | MTNR1BMTNR1A | |
| SCHEMBL3586039 | 0.76 | MTNR1B (0.57) | MTNR1BMTNR1A | |
| SCHEMBL6635131 | 0.75 | MTNR1A (0.49) | MTNR1BMTNR1A | |
| SCHEMBL6636354 | 0.75 | MTNR1B (0.64) | MTNR1BMTNR1A | |
| SCHEMBL6636157 | 0.73 | MTNR1B (0.65) | MTNR1BMTNR1A | |
| SCHEMBL6640765 | 0.72 | MTNR1B (0.60) | MTNR1BMTNR1A | |
| SCHEMBL6632987 | 0.72 | MTNR1B (1.00) | MTNR1BMTNR1A | |
| SCHEMBL7741207 | 0.71 | MTNR1B (0.50) | MTNR1BMTNR1A | |
| SCHEMBL6633694 | 0.71 | MTNR1B (1.00) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047664-B1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |
| EP-1047664-A1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999036392-A1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 1999-07-22 | — | — | WO | disclosed |