Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636828 | 0.83 | TYMS (0.39) | TYMSMEN1KMT2AKDM4EPDGFRB | |
| SCHEMBL6636897 | 0.83 | RAB9A (0.37) | TYMSMEN1KMT2AKDM4EHPGD | |
| SCHEMBL6637345 | 0.77 | GAA (0.39) | TYMSMEN1KMT2AKDM4EPSMD14 | |
| SCHEMBL13956966 | 0.77 | MAPT (0.33) | MEN1KMT2AKDM4ETSHRHTT | |
| SCHEMBL1484558 | 0.76 | ALDH1A1 (0.34) | MEN1KMT2AKDM4EHPGDTSHR | |
| SCHEMBL1484556 | 0.76 | ALDH1A1 (0.34) | MEN1KMT2AKDM4EHPGDTSHR | |
| SCHEMBL501544 | 0.72 | KDM4E (0.32) | KDM4EHPGDALDH1A1GRIN1GRIN2B | |
| SCHEMBL501776 | 0.71 | TYMS (0.35) | TYMSMEN1KMT2AKDM4EPSMD14 | |
| SCHEMBL501300 | 0.70 | KDM4E (0.35) | TYMSMEN1KMT2AKDM4EHPGD | |
| SCHEMBL501116 | 0.68 | TLR7 (0.35) | TYMSMEN1KMT2AKDM4EPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159271-B1 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2004-08-25 | — | — | EP | disclosed |