Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636341 | 0.83 | TYMS (0.39) | TYMSP2RX3MEN1KMT2AKDM4E | |
| SCHEMBL1484512 | 0.77 | SMN1; SMN2 (0.35) | MEN1KMT2AKDM4ETSHRHPGD | |
| SCHEMBL1484755 | 0.76 | SMN1; SMN2 (0.35) | MEN1KMT2AKDM4ETSHRHPGD | |
| SCHEMBL1484757 | 0.76 | SMN1; SMN2 (0.35) | MEN1KMT2AKDM4ETSHRHPGD | |
| SCHEMBL6636897 | 0.69 | RAB9A (0.37) | TYMSMEN1KMT2AKDM4EHPGD | |
| SCHEMBL4864080 | 0.67 | TYMS (0.48) | TYMSMEN1KMT2AKDM4ETSHR | |
| SCHEMBL6086864 | 0.67 | HPGD (0.44) | MEN1KMT2AKDM4ETSHRPSMD14 | |
| SCHEMBL6086545 | 0.67 | HPGD (0.43) | MEN1KMT2AKDM4ETSHRPSMD14 | |
| SCHEMBL6087483 | 0.67 | MEN1 (0.43) | MEN1KMT2AKDM4ETSHRPSMD14 | |
| SCHEMBL6085671 | 0.67 | GRIN1 (0.44) | HPGDMAPK1POLBALDH1A1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159271-B1 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2004-08-25 | — | — | EP | disclosed |