Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 1/20 | 0.39 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087421 | 0.91 | SMN1; SMN2 (0.37) | HPGDKMT2ATSHRKDM4EMEN1 | |
| SCHEMBL6086507 | 0.89 | DAO (0.45) | HPGDKMT2ATSHRKDM4EMEN1 | |
| SCHEMBL6085656 | 0.88 | SMN1; SMN2 (0.33) | HPGDKMT2ATSHRKDM4EMEN1 | |
| SCHEMBL6086881 | 0.87 | SMN1; SMN2 (0.42) | HPGDKMT2ATSHRKDM4EMEN1 | |
| SCHEMBL6087645 | 0.87 | GRIN1 (0.44) | HPGDMAPK1ADORA3ALDH1A1POLB | |
| SCHEMBL6086770 | 0.86 | GRIN1 (0.37) | KMT2AALDH1A1GAATPH1TPH2 | |
| SCHEMBL6088055 | 0.86 | TYMS (0.38) | HPGDKMT2ATSHRKDM4EMEN1 | |
| SCHEMBL6087289 | 0.86 | MTNR1A (0.48) | HPGDKMT2AADORA3HSD17B10POLB | |
| SCHEMBL7854341 | 0.85 | TPH1 (0.33) | HPGDKMT2ATSHRKDM4EMEN1 | |
| SCHEMBL7758840 | 0.85 | ALDH1A1 (0.51) | HPGDKMT2ATSHRKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |