⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660262 | 0.92 | — | — | |
| SCHEMBL4682199 | 0.88 | — | — | |
| SCHEMBL3616280 | 0.86 | HSD11B1 (0.30) | — | |
| SCHEMBL7468947 | 0.85 | HSD11B1 (0.30) | — | |
| SCHEMBL2763357 | 0.84 | — | — | |
| SCHEMBL18191738 | 0.81 | — | — | |
| SCHEMBL5379373 | 0.70 | EPHX2 (0.35) | — | |
| SCHEMBL10706424 | 0.69 | CYP1A2 (0.33) | — | |
| SCHEMBL940485 | 0.66 | SLC6A1 (0.42) | — | |
| SCHEMBL31108911 | 0.66 | NLRP3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061076-B1 | N-ACYL CYCLIC AMINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-12-08 | — | — | EP | disclosed |
| EP-0930298-B1 | FLUORINATED 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| CN-1290251-A | N-acyl cyclic amine derivatives | BANYU PHARMA CO LTD (JP) | 2001-04-04 | — | — | CN | disclosed |
| EP-1061076-A1 | N-ACYL CYCLIC AMINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-12-20 | — | — | EP | disclosed |
| US-6140333-A | FOR TREATMENT AND/OR PROPHYLAXIS OF DISEASES INCLUDE SUCH RESPIRATORY DISEASES AS CHRONIC OBSTRUCTIVE PULMONARY DISEASES, CHRONIC BRONCHITIS, ASTHMA, CHRONIC RESPIRATORY OBSTRUCTION, PULMONARY FIBROSIS, PULMONARY EMPHYSEMA | BANYU PHARMACEUTICAL CO LTD (JP) | 2000-10-31 | — | — | US | disclosed |