Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530096 | 0.83 | CYP1A2 (0.45) | KCNH2SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL8139051 | 0.79 | SMN1; SMN2 (0.53) | KCNH2SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL9690986 | 0.77 | SMN1; SMN2 (0.51) | KCNH2SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL4731396 | 0.76 | KCNH2 (0.40) | KCNH2ALDH1A1ITGB3ITGAVMAPK1 | |
| Hydrochloric Acid SCHEMBL9382986 | 0.76 | SMN1; SMN2 (0.50) | KCNH2SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL383139 | 0.75 | NOS2 (0.58) | KCNH2SMN1; SMN2LMNAALDH1A1ITGB3 | |
| SCHEMBL7416758 | 0.75 | KCNH2 (0.65) | KCNH2SMN1; SMN2 | |
| SCHEMBL9383756 | 0.75 | NPC1 (0.53) | KCNH2SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL6780216 | 0.74 | RAB9A (0.55) | SMN1; SMN2NPC1RAB9APOLBTDP1 | |
| SCHEMBL1598711 | 0.74 | RAB9A (0.52) | SMN1; SMN2NPC1RAB9APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1400519-A1 | Respiratory syncytial virus replication inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-03-24 | — | — | EP | disclosed |