SCHEMBL663701

SCHEMBL663701

CCCCCCC1C=COC1=O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.39
PPARG P37231 2/20 0.38
CES2 O00748 1/20 0.38
POLB P06746 1/20 0.36
FASN P49327 1/20 0.36
DNTT P04053 1/20 0.36
DAGLA Q9Y4D2 1/20 0.36
PRKCA P17252 1/20 0.36
ALDH1A1 P00352 1/20 0.35
NFKB1 P19838 2/20 0.35
NFKB2 Q00653 2/20 0.35
RELA Q04206 2/20 0.35
GRM2 Q14416 3/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3174394 1.00 CYP1A2 (0.39) CYP1A2PPARGCES2POLBFASN
SCHEMBL29222062 1.00 CYP1A2 (0.39) CYP1A2PPARGCES2POLBFASN
SCHEMBL665389 1.00 CYP1A2 (0.39) CYP1A2PPARGCES2POLBFASN
SCHEMBL15152182 0.98 CYP1A2 (0.36) CYP1A2PPARGCES2POLBFASN
SCHEMBL28659621 0.88 CYP1A2 (0.36) CYP1A2PPARGCES2DNTTDAGLA
SCHEMBL6288737 0.84
SCHEMBL11766874 0.76 NFKB1 (0.41) CYP1A2PPARGCES2DNTTALDH1A1
SCHEMBL7925741 0.73 PPARG (0.40) CYP1A2PPARGCES2POLBFASN
SCHEMBL1752692 0.69 KMT2A (0.38) CES2
SCHEMBL663913 0.69 ALDH1A1 (0.38) CYP1A2PPARGCES2DAGLAPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4074807-B1 COMPOSITIONS COMPRISING A FLUOROOLEFIN CHEMOURS CO FC LLC (US) 2025-07-09 EP disclosed
EP-3543310-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-32 CHEMOURS CO FC LLC (US) 2024-07-03 EP disclosed
EP-3299435-B1 METHOD OF PREPARING A COMPOSITION COMPRISING HFC-1234YF CHEMOURS CO FC LLC (US) 2024-06-26 EP disclosed
EP-3309233-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-152A CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
EP-2749623-B2 Method for replacing a high GWP refrigerant in a refrigeration, air-conditioning, or heat pump apparatus CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
US-20230265330-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2023-08-24 US disclosed
US-11674067-B2 Compositions comprising a fluoroolefin THE CHEMOURS COMPANY FC, LLC (US) 2023-06-13 US disclosed
US-20220389297-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2022-12-08 US disclosed
US-20220389298-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2022-12-08 US disclosed
EP-4074807-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN The Chemours Company FC, LLC (US) 2022-10-19 EP disclosed
US-20050151113-A1 Hydrofluorocarbon refrigerant compositions and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050151112-A1 1,1,1,2,2,3,3,4,4-Nonafluoro-4-methoxybutane refrigerant compositions comprising hydrofluorocarbon, and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050151110-A1 Fluoroether refrigerant compositions and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
EP-1551934-A2 REFRIGERANT COMPOSITIONS COMPRISING PERFORMANCE ENHANCING ADDITIVES E. I. du Pont de Nemours and Company (US) 2005-07-13 EP disclosed
US-20050145822-A1 Refrigerant compositions comprising UV fluorescent dye and solubilizing agent E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-07 US disclosed
US-20050127321-A1 Compositions containing lactone compatibilizers E. I. DU PONT DE NEMOURS AND COMPANY 2005-06-16 US disclosed
US-20050109978-A1 Refrigerant compositions comprising performance enhancing additives LECK THOMAS J (US) 2005-05-26 US disclosed
US-6841088-B2 Fluorocarbon, oxygenated and non-oxygenated lubricant, and compatibilizer composition, and method for replacing refrigeration composition in a refrigeration system E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-01-11 US disclosed
US-20040099838-A1 Refrigerant compositions comprising performance enhancing additives E. I. DU PONT DE NEMOURS AND COMPANY 2004-05-27 US disclosed
WO-2004015042-A2 REFRIGERANT COMPOSITIONS COMPRISING PERFORMANCE ENHANCING ADDITIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2004-02-19 WO disclosed