Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | DNTT | P04053 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | PDCD4 | Q53EL6 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397305 | 0.86 | KAT2A (0.30) | — | |
| SCHEMBL11766874 | 0.78 | NFKB1 (0.41) | PPARGDNTTCYP1A2CES2 | |
| SCHEMBL665389 | 0.73 | CYP1A2 (0.39) | PPARGPOLBFASNDNTTCYP1A2 | |
| SCHEMBL3174394 | 0.73 | CYP1A2 (0.39) | PPARGPOLBFASNDNTTCYP1A2 | |
| SCHEMBL663701 | 0.73 | CYP1A2 (0.39) | PPARGPOLBFASNDNTTCYP1A2 | |
| SCHEMBL29222062 | 0.73 | CYP1A2 (0.39) | PPARGPOLBFASNDNTTCYP1A2 | |
| SCHEMBL15152182 | 0.70 | CYP1A2 (0.36) | PPARGPOLBFASNDNTTCYP1A2 | |
| SCHEMBL28659621 | 0.66 | CYP1A2 (0.36) | PPARGDNTTCYP1A2CES2 | |
| SCHEMBL4021367 | 0.62 | DNTT (0.42) | PPARGDNTTCYP1A2CES2 | |
| SCHEMBL6235486 | 0.62 | DNTT (0.36) | PPARGPOLBDNTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748626-B1 | PATCH CONTAINING ISOSORBIDE DINITRATE AND PREPARED BY USING ADHESIVE MIXTURE | TEIJIN LTD (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-5762954-A | COMPRISES A PRESSURE SENSITIVE ADHESIVE LAYER FORMED ON A FLEXIBLE SUPPORT, ADHESIVE BEING COMPOSED OF POLYSILOXANE AND COPOLYMER OF VINYL ACETATE, AND ISOSORBIDE DINITRATE; USEFUL FOR DRUG DELIVERY; SUSTAINED RELEASE | TEIJIN LIMITED (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0748626-A1 | PATCH CONTAINING ISOSORBIDE DINITRATE AND PREPARED BY USING ADHESIVE MIXTURE | TEIJIN LIMITED (JP) | 1996-12-18 | — | — | EP | disclosed |
| US-5470563-A | Polyethersiloxane | SHISEIDO COMPANY LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0266921-A2 | Skin irritation alleviation agent and composition thereof | SHISEIDO COMPANY LIMITED (JP) | 1988-05-11 | — | — | EP | disclosed |