Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6638820 | 0.80 | POLB (0.35) | EDNRAPOLBCACNA1DMAPT | |
| SCHEMBL6679547 | 0.73 | HDAC4 (0.33) | EDNRAPOLB | |
| SCHEMBL6637467 | 0.71 | CACNA1D (0.35) | CACNA1DMAPT | |
| SCHEMBL6536023 | 0.68 | — | — | |
| SCHEMBL6677869 | 0.67 | CACNA1D (0.31) | CACNA1D | |
| SCHEMBL23435303 | 0.66 | ALDH1A1 (0.40) | EDNRAPOLBCACNA1D | |
| SCHEMBL6677411 | 0.65 | ATM (0.33) | EDNRAPOLBCACNA1DMAPT | |
| SCHEMBL6678116 | 0.65 | — | — | |
| SCHEMBL6681681 | 0.64 | HDAC4 (0.32) | — | |
| SCHEMBL6678100 | 0.64 | CACNA1D (0.33) | CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |