Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 9/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635742 | 0.90 | SOAT1 (0.45) | EDNRB | |
| SCHEMBL7610547 | 0.89 | EDNRB (0.49) | EDNRBHSD17B10PTGDR2 | |
| SCHEMBL6636299 | 0.81 | PADI4 (0.47) | EDNRBUSP2LMNAHSD17B10PTGDR2 | |
| SCHEMBL6640973 | 0.79 | ACAT1 (0.52) | EDNRBHSD17B10 | |
| SCHEMBL6638660 | 0.78 | ACAT1 (0.49) | EDNRBHSD17B10 | |
| SCHEMBL8325752 | 0.77 | PDE4A (0.49) | KMT2AMEN1 | |
| SCHEMBL6634385 | 0.76 | EDNRB (0.46) | EDNRBRXFP1 | |
| SCHEMBL7613883 | 0.76 | ACAT1 (0.46) | EDNRB | |
| SCHEMBL6636150 | 0.76 | EDNRB (0.49) | EDNRBUSP2CASP1CASP7LMNA | |
| SCHEMBL6639134 | 0.74 | EDNRB (0.44) | EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842933-B1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMA (JP) | 2004-08-04 | — | — | EP | disclosed |
| US-5843957-A | Naphthyridine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0842933-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-05-20 | — | — | EP | disclosed |